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Gastrointestinal symptoms (more common with oral preparations): Mild nausea or upset stomach Diarrhoea (typically with very high doses) Other effects: Headache, particularly when treatment is first initiated Dizziness or light-headedness Skin reactions such as mild rash or itching Temporary reddish discolouration of urine (chromaturia) after hydroxocobalamin injections, which is harmless It is important to note that many symptoms attributed to B12 supplementation may actually represent the body's response to correcting a deficiency

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1 Why NAD+ and Mitochondrial Function Matter Maintaining enough NAD+ is crucial because it activates several important processes, including: 7 Cellular signaling and metabolic regulation Cellular energy production and oxidative metabolism DNA repair enzymes and sirtuin (proteins that protect and repair) activity Mitochondria need a constant supply of NAD+ to make ATP

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